Prime objective of this lecture is to present on Variation in Chromosome Number. Changes in chromosome number can occur by the addition of all or part of a chromosome (aneuploidy), the loss of an entire set of chromosomes (monoploidy) or the gain of one or more complete sets of chromosomes (euploidy). Nullisomy – loss of one homologous chromosome pair. (e.g., Oat); Monosomy – loss of a single chromosome (Maize); Trisomy – one extra chromosome. (Datura) and Tetrasomy – one extra chromosome pair.