Chemistry

Monopotassium Glutamate

Monopotassium Glutamate

Monopotassium glutamate (MPG) is the compound with formula KC5H8NO4. It is a chemical compound that is a potassium salt of glutamic acid, similar to monosodium glutamate (MSG). It is a potassium salt of glutamic acid. It is used as a flavor enhancer in food, providing an umami taste.

It has the E number E622 and is used in foods as a flavor enhancer. It is a non-sodium MSG alternative. It consists of the glutamate anion and a potassium cation (K⁺), replacing sodium in MSG.

Properties

  • Chemical formula: C5H8KNO4
  • Molar mass: 185.220 g·mol−1
  • Appearance: White crystalline powder
  • Solubility: Highly soluble in water
  • pH (1% solution): ~7
  • Melting Point: Decomposes on heating
  • Taste: Umami (savory)
  • Stability: Stable under normal conditions

Natural Occurrence

Monopotassium glutamate itself is not commonly found in nature in pure form, but glutamic acid and its salts (like MPG) are naturally present in:

  • Protein-rich foods (as glutamate): Seaweed (e.g., kombu), Aged cheeses, Tomatoes, Mushrooms, Meat and fish
  • Fermented foods: Soy sauce, Miso, Fermented bean paste

In these sources, potassium salts may naturally occur, but industrial MPG is synthesized by neutralizing glutamic acid with potassium hydroxide (KOH).

Use in Food

  • MPG is used as a flavor enhancer, just like MSG.
  • It provides the umami taste — a savory flavor common in meats, broths, and mushrooms.
  • It’s sometimes used as a low-sodium alternative to MSG, especially for those needing to limit sodium intake.

Applications Beyond Food

  • Occasionally used in biochemical research or nutritional formulations.
  • Acts as a source of potassium and glutamate, which are essential for cellular functions.

Regulation

  • Generally Recognized As Safe (GRAS) when used in reasonable amounts.
  • Overconsumption can lead to the same concerns as MSG (e.g., “Chinese Restaurant Syndrome”), although evidence is limited.
  • High potassium intake may be a concern for individuals with kidney problems.

Health & Safety

Generally recognized as safe (GRAS) by regulatory agencies when consumed in typical amounts. Like MSG, it may cause sensitivity reactions in a small subset of people (e.g., headaches, flushing), though scientific evidence of widespread sensitivity is limited.