Basic purpose of this lecture is to present on Price of Drug Addiction. Here briefly focus on how Drug Affect Dopamine Levels. Dopamine is thought to be the master molecule of addiction. It is made in the brain and affects primitive parts of the brain. Cigarettes contribute to death rates from cancer and heart disease. Alcohol is the leading cause of violence. Needles are spreading AIDS. Addiction to drugs, cigarettes and alcohol account for a third of all hospital admissions, and a majority of all crimes. Drug use costing us excess of 240 billion dollars annually.