Chemistry

Calcium Pangamate

Calcium Pangamate

Calcium pangamate is a mineral supplement. It is sometimes used as a synonym for pangamic acid. It was originally marketed as a supplement with various health benefits, particularly for its potential to support cardiovascular health, improve mental clarity, and enhance oxygen utilization. It is also sometimes promoted for its purported benefits in physical performance, mental function, and general wellness.

Properties

  • Appearance: White or off-white crystalline powder.
  • Solubility: It is soluble in water, forming a slightly acidic solution.
  • Molecular Weight: Typically, the molecular weight of calcium pangamate depends on its exact form and hydration state but falls around 324.3 g/mol.
  • Stability: It is generally stable under normal conditions of temperature and pressure.
  • pH: The compound tends to form a slightly acidic solution in water.

Occurrence

Calcium pangamate does not naturally occur in significant amounts but is synthesized for use in supplements and certain health applications. It is often produced as a compound derived from pangamic acid (dimethylglycine, DMG), which is a natural substance found in trace amounts in foods such as:

  • Whole grains
  • Liver
  • Legumes
  • Mushrooms
  • Seeds

However, these foods contain relatively low levels of DMG, and supplemental forms of calcium pangamate are often used to achieve higher doses for health benefits.

Uses and Applications

  • Dietary Supplement: Calcium pangamate is often marketed as a supplement that may support various bodily functions, particularly in improving mental and physical performance, reducing fatigue, and enhancing the immune system.
  • Sports Performance: Some people use it for its potential to improve stamina and endurance, though scientific evidence on its effectiveness is limited.
  • Health Benefits: It is also sometimes promoted for improving cardiovascular health, regulating blood sugar levels, and supporting detoxification. However, these benefits are more anecdotal, and research on its efficacy is still ongoing.

Safety and Side Effects

Although it has been used in various health supplements, scientific research on the effectiveness and safety of calcium pangamate is limited. Some users report mild side effects such as headaches or digestive upset, though these are generally considered rare. It is always advisable to consult with a healthcare provider before starting any new supplement.