General purpose of this article is to explain Role of Grameen Bank on Poverty Alleviation. This major goal of virtually any developmental intervention in Bangladesh can be alleviation of poverty. The economy of Bangladesh that has a large and rapidly developing population and low for each capita income reveals condition of abject poverty for most people. The task of poverty alleviation with all the ultimate aim of its eradication is often a challenging one. The major causes of poverty in Bangladesh tend to be low economic growth, inequitable submitting of income, unequal submitting of productive assets, unemployment and underemployment, high rate of population growth etc. Grameen Bank is most beneficial known as an operating model of targeted, small scale farm credit. Grameen is also a model of an experimental learning business organization work for Poverty Alleviation.