General purpose of this study is to present on Cholera Disease. Cholera is an infection in the small intestine caused by the bacterium Vibrio cholerae. When an adequate quantity of the bacteria has passed into the stomach in food, they accumulate and begin to produce poisonous substances. The main symptoms are profuse, watery diarrhea and vomiting. Transmission occurs primarily by drinking water or eating food that has been contaminated by the feces of an infected person, including one with no apparent symptoms.